the rate of heart attacks and strokes, or deaths.
“This was a fairly definitive assessment, and in this group of older type 2 diabetes patients, there’s no evidence of a legacy effect,” Reaven said. “Our data suggests that for glucose-lowering to have continued benefit, it must be sustained.”
Since the intervention portion of the study was done, newer medications — some that have specifically been shown to reduce the risk of heart disease — have been introduced for type 2 diabetes. It’s not clear what the long-term effect of these medications might be, or if these newer drugs have a legacy effect.
Results of the study were published June 6 in the New England Journal of Medicine.
Dr. Kasia Lipska from Yale School of Medicine is co-author of an
