Obesity Could Worsen MS Disability

levels of inflammation in the central nervous system, and levels of cholesterol and triglycerides.

They found that obese patients have higher levels of two proteins that promote inflammation — interleukin-6 and leptin, which is produced by fat cells. Excessively heavy patients also had lower levels of interleukin-13, an anti-inflammatory agent.

Higher triglycerides and higher HDL cholesterol previously have been linked to higher IL-6 levels, the researchers pointed out.

“This study confirms that obesity is associated with greater symptomatic severity of relapsing-remitting multiple sclerosis,” said study co-author Dr. Mario Stampanoni Bassi, a neurologist at Neuromed Mediterranean Neurological Institute in Pozzilli, Italy.

“Our results therefore suggest that excessive body weight, or altered lipid profile, are associated to

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