New Migraine Drug Might Help When Other Meds Don’t

Man in a suit touches his head in pain

sound. Just under 38% of rimegepant users were free of their most bothersome symptom within two hours. That compared with 25% of placebo users.

As for safety, Colman said the findings were “reassuring.” After a single dose, just under 2% of rimegepant patients had nausea, and 1.5% developed a urinary tract infection.

There are still questions, though, Colman said. “This trial looked at a single treatment,” she noted. “Does the drug continue to be effective over time? Consistency is important.”

It would also be helpful, Colman said, for studies to focus on patients who’d failed to benefit from triptans, or who cannot take the drugs.

A separate trial in the same journal focused on cluster headaches — a rare

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