Low Blood Sugar Is Just As Dangerous As High Blood Sugar

Keeping blood sugar levels within a safe range is key to managing both type 1 and type 2 diabetes. In a new finding that could lead to fewer complications for diabetes patients, Yale School of Medicine researchers has found that changes in the size of mitochondria in a small subset of brain cells play a crucial role in safely maintaining blood sugar levels.

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“Low blood sugar can be as dangerous as high blood sugar,” said senior author Sabrina Diano, professor in the Departments of Obstetrics, Gynecology & Reproductive Sciences, Neuroscience, and Comparative Medicine. “We’ve found that changes in the size of mitochondria — small intracellular organelles responsible for energy production — in certain cells in the brain, could be key to maintaining the blood sugar within a safe range.”

“This new finding adds to our understanding of how the body keeps blood sugar levels within a safe range when sugar levels drop, like during fasting, or when they spike after a meal,” Diano added.